For people in Costa Mesa, California struggling with opioid use disorder, medication-assisted treatment (MAT) is the evidence-based standard of care. MAT combines FDA-approved medications — buprenorphine, methadone, or naltrexone — with counseling and behavioral therapy, and it cuts the risk of fatal overdose by roughly half compared to counseling alone. For severe opioid use disorder, it is the most effective treatment available.
Buprenorphine (including Suboxone and Subutex) is the most widely prescribed MAT medication in Costa Mesa. It is a partial opioid agonist that binds to opioid receptors without producing the euphoric high of full opioids, enough to prevent withdrawal and manage cravings without creating a dangerous overdose risk. Because of a 2023 federal rule change, buprenorphine can now be prescribed by any licensed clinician with a standard DEA registration, which has dramatically expanded access in communities like Costa Mesa.
Methadone treatment is also available through federally regulated opioid treatment programs (OTPs), which provide daily observed dosing along with counseling and case management. Naltrexone (including the Vivitrol monthly injection) is a third option that works by blocking opioid receptors entirely — it produces no physical dependence but requires a full detox before starting. The right choice depends on your situation, your history, and your goals.
Liberation Way's free, confidential helpline can help you understand your MAT options in Costa Mesa and connect you with a program that has admissions capacity. A treatment specialist will walk you through insurance and cost questions and help you find a program that fits your needs. Call (866) 275-3142 any time, day or night.
925 Victoria Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxPrivate Insurance
725 Center Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxPrivate Insurance
693 Plumer Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxOutpatientIOPDual DiagnosisPrivate InsuranceTricare
1509 Orange Avenue A, Costa Mesa, CA, 92627
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546 Bernard Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxDual DiagnosisPrivate InsuranceVeteransPregnant WomenLGBTQ+
550-A Bernard Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxDual DiagnosisPrivate InsuranceVeteransPregnant WomenLGBTQ+
548 Bernard Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxDual DiagnosisPrivate InsuranceVeteransPregnant WomenLGBTQ+
550-B Bernard Street, Costa Mesa, CA, 92627
Buprenorphine/SuboxoneMATDetoxDual DiagnosisPrivate InsuranceVeteransPregnant WomenLGBTQ+
1119 Sunflower Avenue, Costa Mesa, CA, 92627
MATDual DiagnosisPrivate InsuranceMedicareTricareVeteransLGBTQ+
546 Hamilton Street, Costa Mesa, CA, 92627
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317 Rochester Street, Costa Mesa, CA, 92627
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373 Ralcam Place, Costa Mesa, CA, 92627
MATDual DiagnosisPrivate InsuranceMedicareTricareVeteransLGBTQ+
2028 Fullerton Avenue, Costa Mesa, CA, 92627
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154 and 160 East Bay Street, Costa Mesa, CA, 92627
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1219 Parnell Place, Costa Mesa, CA, 92626
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3132 Boston Way, Costa Mesa, CA, 92626
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3132 Boston Way, Costa Mesa, CA, 92626
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2738 Lorenzo Avenue, Costa Mesa, CA, 92626
Buprenorphine/SuboxoneMATDetoxPrivate Insurance
3062 Johnson Avenue, Costa Mesa, CA, 92626
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334 University Avenue, Costa Mesa, CA, 92627
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2607 Willo Lane, Costa Mesa, CA, 92627
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559 Pierpont Drive, Costa Mesa, CA, 92626
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3151 Airway Avenue, Costa Mesa, CA, 92626
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3151 Airway Avenue, Costa Mesa, CA, 92626
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