Medication-assisted treatment combines FDA-approved medications with counseling and behavioral therapy to treat opioid use disorder. It is the evidence-based standard of care and has been shown to cut overdose mortality by roughly half compared to counseling alone.
Liberation Way's directory lists 9,222 medication-assisted treatment providers across the United States, including office-based buprenorphine prescribers, federally regulated opioid treatment programs (methadone clinics), and addiction medicine practices offering Vivitrol (extended-release naltrexone). Information is compiled from SAMHSA's public data on treatment facilities and updated regularly.
MAT uses one of three FDA-approved medications — buprenorphine, methadone, or naltrexone — alongside counseling and behavioral therapy. Each medication works differently, and the right choice depends on your situation, history, and goals. Buprenorphine (including Suboxone and Subutex) is the most widely prescribed, partially activating opioid receptors to prevent withdrawal and manage cravings without a dangerous overdose risk. Methadone, available through licensed opioid treatment programs, is the most effective option for severe, long-standing dependence. Naltrexone (Vivitrol) blocks opioid receptors entirely and is given as a monthly injection after a full detox.
The American Society of Addiction Medicine, SAMHSA, the CDC, and the World Health Organization all recommend MAT as first-line treatment for opioid use disorder. If you are not sure which approach fits your situation, our helpline can help you understand the tradeoffs and connect you with a provider.
Speak with a treatment specialist 24/7. We can help you understand the differences between buprenorphine, methadone, and naltrexone, and find a provider that matches your needs.
Call (866) 275-3142Free, confidential, and available whenever you need it. One phone call is all it takes to start finding your way forward.
Call (866) 275-3142